Stratum corneum
The composition of lanolin resembles the intercellular lipids of the stratum corneum. This is the outermost layer of the skin, which consists of cholesterol, cholesterol derivatives and free fatty acids.
These lipids play a crucial role in the skin’s moisture control. Under normal conditions, water continuously evaporates from the skin's surface.
Insufficient rehydration from lower epidermal layers leads to a dry, inflexible and brittle stratum corneum.
Bi-functionality of lanolin
Lanolin owes its outstanding emollient qualities to the fact that in addition to its semi-occlusive capabilities, it is also capable of allowing the bi-directional transportation of water.
Lanolin Alcohol's water absorption capacity makes it an excellent sole emulsifier. Blended at 6 % into a petroleum jelly based ointment more than 200 % water absorption can be reached. Considering petroleum jelly's close to zero water absorption capacity this converts into almost 3.000 % water absorption for the Lanolin Alcohol in this matrix.
Anhydrous lanolin can absorb more than 200% of its weight in water (WW) to form stable water-in-oil (w/o) emulsions. It's also capable of redistributing this moisture to environments of low relative humidity.
In other words, it can both prevent moisture loss and rehydrate. This can be illustrated with a simple experiment.
Glass sheet experiment
By coating a sheet of glass with a thin film of lanolin and dipping it into a container filled with water, the formerly transparent wax layer grows increasingly opaque because of all the water it has absorbed.
When the glass sheet is removed from the container and exposed to the air, the lanolin film gradually becomes transparent again as it releases the water via evaporation and dries out.
Hydrocarbon-based emollients such as Vaseline or petrolatum do not possess this bi-directional water transport ability. Instead they form an almost impermeable occlusive film on the surface of the skin.
Lanolin, as an auxiliary emulsifier, also helps to improve the smooth feel and silky texture of such oil-based systems.
Similarities between lanolin and human skin
Variations of the glass sheet experiment on the stratum corneum of human skin treated with lanolin have shown similar effects.
In addition to the chemical similarity between lanolin and human skin lipids, other physical similarities have been discovered, such as multilamellar structures. These molecular aggregations strongly resemble the liquid crystal structures occurring in skin lipids.
Lanolin-based skin-care products owe their superb emollient properties to the unique chemical and physical characteristics of lanolin.